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Moderna, Inc. (MRNA)

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144,27+1,01 (+0,71%)
Al cierre: 04:00PM EDT
143,76 -0,51 (-0,36%)
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  • H
    Hank
    $MRNA conversation
    Can't wait till $MRNA comes out with another drug using their technology.
  • N
    Nick
    $BNTX conversation
    I’m looking to put my savings in $bntx or $mrna. I prefer bntx because of their management, but mrna has just came with good results on covid booster for fall. 😩 hard choice. any good comments would be appreciated.
  • S
    Stark
    $NVAX conversation
    So now we have two mRNA vaccines approved for young children. Truth is that if you have a active child that attended school , was involved in activities, interacted with friends the child most likely has had Covid. Most it appears had very mild or no symptoms.
    That means they have natural immunity and if the fall variant is highly contagious but no more virulent they are well protected going into the fall and there would be no need for them to get vaccinated and exposed to the possible short and long term side effects of mRNA. If the fall variant is a much more virulent strain or if the child is immune compromised I would then consider that the benefit might be worth the risk . At the present time the vaccine I would personally choose for my child in that scenario would be Nuvaxovid, the vaccine is a traditional protein based vaccine that has none of the potential short and long term side effects of the mRNA vaccines. The dosage is the same as in both adults and children with a most likely higher and more durable immune response than adults.
    Since we don’t have that choice yet and you only have mRNA vaccines, the differences in the two mRNA vaccines must be considered. The Pfizer vaccine is a very low dose vaccine that has a minimal and rapidly waning immune response. The dosage was picked to minimize side effects not to initiate a efficacious and durable protection. In healthy children especially those that most likely had a prior Covid exposure the vaccine is USELESS, yes I again make that claim. If trying to protect a child that actually would benefit from vaccine protection it gives false hope.
    For the high risk child in that situation, it would be wise to choose The Moderna higher dose vaccine which will give the child protection against severe illness and death.
    These vaccines will be pushed hard on children and most go along with the company line and lies. They will be advertised, talking heads on TV , internet will encouraging vaccines for all children. You are hearing the truth , I wonder if the pediatricians will push back on that?? As a group they are far more protective of their young patients. We shall see.
    $bntx $mrna
  • J
    Juan
    $MRNA conversation
    Unanimous yes FDA vote for moderna $MRNA vaccine to 6-11 year olds
  • T
    Titos
    $NVAX conversation
    Bo, I am usually reasonably confident with my non-bullish posts on NVAX but this one is a little on the speculative side. This one post you bullish folks can fairly just brush off as me just being biased and overall not very positive on novavax's prospect but I'll share my thoughts anyway and here goes: I think regulators will not easily accept novavax's vaccine as a tweakable platform to accomodate for omicron AT LEAST NOT AS EASILY as they may do for $MRNA later this month. My contention is that changing protein sequences to accomodate for variants also bear the "risk" of changing a protein-based vaccine's physicochemistry and biological character, especially when their formulation contains exposed proteins displayed on its surface. This may in turn affect tissue distribution. One may argue such minor changes to the protein will not be enough to bring out such an effect, an argument which I take as fair and most likely true. But the theoretical risk that it does is there for sure. At the very least, I believe regulators will want to see them repeat tissue distribution for the preclinicals for every of their tweaks. If novavax is smart, they will have this data prepared before hand. Its not that difficult to do to begin with but it is not assuring at all to know that they did not even have the tissue distribution data for the original version in January 2022 as TGA still had to request this follow up data from them in their approval documents. Read: Australian Public Assessment Report for SARS-CoV-2 rS with Matrix-M adjuvant. Imagine that they started their effort in 2020 but that they had not completed preclinicals for tissue distribution in January 2022. I am really interested to see how that data looks like. I want to compare that to the distribution of mRNA vaccine.
  • T
    Titos
    $NVAX conversation
    To those spinning that myocarditis is really as a non-issue for Novavax, this was Dr. Paul Offit's statements (FDA video timestamp 5:33:40): I agree with the FDA's assessment that that handful of cases of myocarditis that occurred within 3 or 4 days of receipt of the second dose of vaccine in young men is consistent with what was seen with the MRNA induced myocarditis. So I think that it's A CAUSAL NOT A COINCIDENTAL ASSOCIATION. Its also interesting in the documents that the FDA handed out to us that they referred to a 2020 paper where there was suspected molecular mimicry between SARS-CoV-2 and the heavy chain of alpha myosin cardiac muscle cells. If that's true, you would argue that all COVID vaccines, as well as COVID itself, should cause myocarditis, but that may well not be true. We really need to know whether or not this is true for the vector virus vaccines like J&J or Astrazeneca. We need to know this is true for vaccines that have been administered to millions of people, or for the Corbavax vaccine, a truncated protein given out to many people in India. I think it's incumbent upon us to know whether it's about the protein itself or whether it's about the way the protein is being processed, so that we can use that knowledge to make safer vaccines for a disease that is going to be with us for decades, if not longer. $MRNA $BNTX
  • T
    Titos
    $MRNA conversation
    WSJ today: "Novavax’s New Covid-19 Vaccine Might Be Late to the Party". A nice insight on the months and years to come for $MRNA and $BNTX.
  • G
    Great White Shaak
    $NVAX conversation
    It’s happening, Takeda is launching safer $nvax in Japan. It’s the end of $TAK assistance to $MRNA for Spikevax in 🇯🇵.

    Takeda and Moderna Announce Plans to Transfer Marketing Authorization for Spikevax™ COVID-19 Vaccine in Japan to Moderna. I predicted this day will come (yesterday), more countries will follow and abandon the Mrna vaccines as they increase NVAX2373. Sorry GR8, your fired
  • B
    Bryan
    $MRNA conversation
    OMG, $MRNA is mooning!!
  • T
    Titos
    $MRNA conversation
    News regarding our competitor: "The FDA also flagged the possible risk of myocarditis, a type of heart inflammation also associated with rival mRNA vaccines, after the Novavax shot. There were four cases of myocarditis in the trial within 20 days post vaccination." Folks who follow my post probably can remember than I predicted this announcement will happen for them. The Novastans are really clueless about what they post on the scientific front. $BNTX $MRNA
  • m
    mint
    Novavax, Inc.
    I did copy that @Novavax, please, Please, PLEASE put out some Press Releases!!

    South Korea is now paying out medical claim settlements for those individuals who die or get injured die to pericarditis from one of the #mRNA vaccines.

    That makes Novavax the safest vaccine in S Korea!!

    @US_FDA
  • M
    Mr. Shockey II
    $QQQ conversation
    Today's rally is very suspect, led by laggards like $DOCU $NFLX $PTON $MRNA $ZM. FADE!
  • S
    Stark
    $NVAX conversation
    It is a zero sum game now and yes I do believe now with near 100% conviction that mRNA has failed not only in Covid but in its entire infectious disease platform. The more studies that are published, the more observational data, the more real world data, the opinions of experts and what is said hinting between the lines, casual statements from the management of the main Biotech companies. All of this combined with my 25 plus years of successful biotech investing convinces me of the failure of mRNA. I was at 95% conviction.
    I know keep bringing this up on various boards , more to see if anybody has a counter to me . When Novavax management stated that the pediatric and adult dose were the same Without additional side effects this was huge. mRNA is dosage restricted, higher the dosage more side effects, lower the dosage and loses efficacy. Catch 22 problem. Novavax in addition to all other benefits Does not have this restriction!!
    Other mRNA vaccines? Entire platform for infectious disease ?
    Yes all of them study after study showing limitations. Don’t know why when I bring up the failed HIV mRNA vaccine and dead monkeys my posts get deleted. Hundreds of posts deleted. Why because after a year of seven high dosage vaccine in a monkey study for hiv , the monkeys had 1-2 months of protection and died of AIDS . Why would any human take that vaccine?
    Flu failure no better efficacy than standard Fluzone, wanes quickly. Same pattern, short lived nabs, high side effects, wanes rapidly. Over and over.
    Increase the dose a little higher side effects, decrease the dose lose efficacy.
    Let’s look closer at that pediatric vaccine that BioNTech has. I went over with another poster on how pediatric dosage is calculated from a premature infant of 22 weeks with a weight of 1 pound to a 500 pound adult , going into old age of over a hundred years old . The kidneys., liver , brain , lungs go from being very immature to aging and failing. Volume of water , muscle fat in the body also changes the dosage, medications that a person is on also effects this. It gets even more complicated than that.
    So why is the BioNTech/Pfizer pediatric Covid vaccine so worthless? They lowered the dosage based on side effects not immune response!!
    11 years old 100 pounds you get 10 mcg. 12 year old 100 pounds you get 30 mcg. Very little if any difference in how a healthy 11 and 12 year old of the same weight would need a different dosage.
    So as you would suspect after 2 months efficacy for Covid in the 12 year old was 67%. The 11 year old dropped to a worthless 11% . Dosage was reduced not on efficacy but on side effects!
    Get it now.
    In time and I think in less than 6 mo this we will have real world data that proves all of this
    If I’m wrong Novavax will be 10 bucks.
    If right 200-300 dollars, you have to place your bets now.
    All an opinion of course , I’m hoping Novavax meets these expectations for the good of world public health hoping we get Covid a little better under control. Certainly mRNA has fallen far short.
    $bntx. $mrna
  • J
    Joyce
    Moderna, Inc.
    How long will the retaliatory adjustment last $MRNA $VENA
  • A
    Amy B.
    I can see either $MRNA or $PFE go for $TNXP preclinical monkey pox vaccine TNX-801 as it is THE ONLY monkey pox vaccine at preclinical level for partnership/buyout? The JYNNEOS Is not made in America - imports here does not solve the problem. Big bar@a will junk all over this
  • T
    Titos
    $MRNA conversation
    The Crotty preprint I shared a month or two ago is now available as a proper peer-reviewed article in the prestigious scientific journal Cell: "Humoral and cellular immune memory to four COVID-19 vaccines." Its obvious now from the data that the claim of superior durability for Novavax does not hold water. When I shared the article in preprint form, someone from the NVAX board tried to refute it by saying that the schedule of dosing and examination were not proper for NVAX. But Figure 1b of the paper in peer reviewed form has now clarified that NOT only that the scheduling was proper, it actually gave Novavax an unfair advantage but it still lost to mRNA vaccine anyway in term of durability. For those who do not know Prof. Shane Crotty, he is a giant in the vaccine study field whose article in 2020 lead Dr. Fauci to believe that it was really possible to prepare a vaccine for Covid-19. There was even a famous photo of Dr. Fauci waving a print of that article in congress to law makers. Crotty's study and insights count as a loud voice that regulators respect. $MRNA $BNTX
  • v
    valuegeek77
    $BNTX conversation
    Why does BNTX trade at such huge discount to $MRNA?

    BNTX is lot more profitable, lot more diversified and lot more PH3 candidates in other areas, much lower PE and comparable growth
  • A
    Amy B.
    Moderna’s looking for a vaccine at preclinical level and guess who has the ONLY VACCINE at thet level made in USA to buy that’s right $TNXP $MRNA
  • J
    Joyce
    Moderna, Inc.
    No need to understand US stocks $MRNA $VENA
  • P
    Paul_Sha
    Moderna, Inc.
    Research is now underway on an investigational #mRNA treatment that could potentially correct the cause of glycogen storage disease type 1a, or #GSD1a, by teaching the body to break down glycogen and improve low fasting blood #glucose. https://t.co/p3lLounHc5